Valproate Toxicity

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Reversible vertical gaze palsy in sodium valproate toxicity.

W e read with interest the report on corticobasal syndrome by Rajagopal et al (1). At times, this neurodegenerative disorder may lead to vertical gaze palsy. We evaluated a patient with valproate toxicity and hyperammonemia and reversible vertical gaze palsy. A 56-year-old man presented with progressive unsteadiness, drowsiness, and cognitive decline for the past 6 months. Twenty-five years pre...

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Ellagic acid modulates sodium valproate induced reproductive toxicity in male Wistar rats.

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Sodium valproate syrup, Sodium valproate syrup India, Sodium valproate syrup manufacturers India

Note:-We are committed to helping you find the right answers to your questions and concerns. However, this Report is not intended to give investment advice, promote the use of Taj Pharmaceuticals Ltd products or provide information on which to base medical treatment. If you have questions regarding any Taj Pharmaceuticals Ltd product or are experiencing a medical emergency, please consult your ...

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Nitroso-urea-cisplatin-based chemotherapy associated with valproate: increase of haematologic toxicity.

BACKGROUND The incidence of haematologic toxicity of valproate (VPA) ranges from 1% to 32% and consists mainly of asymptomatic, dose-dependent thrombopenia. We describe a potentiation of haematologic side-effects of nitroso-urea (NU) when prescribed in association with VPA. PATIENTS AND METHODS We followed a cohort of 70 patients (58 men, 22 women, mean age: 56 years, range 20-75 years). Pati...

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Idiosyncratic reactions to valproate. Clinical risk patterns and mechanisms of toxicity.

Make more knowledge even in less time every day. You may not always spend your time and money to go abroad and get the experience and knowledge by yourself. Reading is a good alternative to do in getting this desirable knowledge and experience. You may gain many things from experiencing directly, but of course it will spend much money. So here, by reading idiosyncratic reactions to valproate cl...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 1990

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-4-4-11